Drugs in the fibrate family are used to improve levels of cholesterol and related lipids found in the blood. Fibrates are particularly helpful for individuals with high levels of triglycerides.
Medications in this category include:
- Clofibrate (Atromid-S)
- Gemfibrozil (Lopid)
- Fenofibrate (Tricor)
Fibrate drugs are known to raise homocysteine levels in the blood. High levels of homocycsteine have been associated with increased risk of heart disease, although a direct connection has not been proven.
Fibrate drugs are known to increase the "blood thinning" effects of drugs in the warfarin (Coumadin) family. Certain herbs, such as garlic, danshen, devil’s claw, dong quai, papaya, PC-SPES and red clover, may thin the blood in a manner somewhat similar to warfarin. Although no such interactions have yet been reported, it is at least theoretically possible that combined use of these herbs and fibrate drugs could pose a risk of bleeding problems.
- Reviewer: EBSCO CAM Review Board
- Review Date: 07/2012 -
- Update Date: 07/25/2012 -